| Type: |
Pathological Analysis Equipments |
Brand Name: |
MEL |
Place of Origin: |
Shanghai, China (Mainland) |
Model Number: |
cassette |
Certification: |
CE/ISO9001/ ISO13485 |
Method: |
lateral flow test |
Sensitivity: |
99.8% |
Overall agreement: |
99.2% |
Specificity: |
99.4% |
Expiration date: |
24 months |
Storage: |
2 to 30 Centigrade |
Specimen: |
W/P/S |
|
Cancer Diagnosis/AFP Test Kit/Tumor Marker Test/AFP Test
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. [4]
The human fetus has the highest amount of AFP levels found in humans. These AFP levels gradually decrease after birth down to the low, but detectable levels found in adults by the time a newborn reaches 8 to 12 months. AFP has no known function in healthy adults. In normal fetuses, AFP binds the hormone estradiol. AFP is measured in pregnant women, using maternal blood or amniotic fluid, as a screening test for a subset of developmental abnormalities: It is principally increased in open neural tube defects and omphalocoele & decreased in Down syndrome. It is also measured in non-pregnant women, other adults, and children, serving as a biomarker to detect a subset of tumors. In adults, levels over 500 nanograms/milliliter of AFP are seen in only three situations: Hepatocellular carcinoma, Germ cell tumors, and metastatic cancer in the liver originating from other primary tumors elsewhere.
In rats, AFP binds maternal estrogen, preventing its passage through the placenta. The main function of this is to prevent the masculinization of female fetuses. The system can be overridden with massive injections of estrogen, which swamp the AFP system and masculinize female fetuses.
Cancer Diagnosis/AFP Test Kit/Tumor Marker Test/AFP Test
http://melsonmedical.en.made-in-china.com/product/LBaQXodMbUkn/China-Cancer-Diagnosis-Afp-Test-Kit-Tumor-Marker-Test-Afp-Test.html
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